Skip the excel row if it's used in script and then move another

Suppose in excel file has 5 rows and first rows has the header. 2nd row data used in script (I mean record had added using this row in the application). I need to check if record is added into application then move to another row till last row and if found data doesn’t use then create the record in the application using that row of data.

Thank you in advance for quick reply.