Maybe I don’t understand, but you can set a Global Variable the same as any variable within your project. If the Global Variable never changes, then just set it with the value in the Profile. If you want it to change, then do like below.
GlobalVariable.gSiteUrl = "https://www.sears.com"
WebUI.navigateToUrl(GlobalVariable.gSiteURL)
WebUI.waitForPageLoad(10)